Manitoba HIV Research Group University of Manitoba
   





Partners













 

Jody Berry

Email: Jody_Berry@phac-aspc.gc.ca

Trainings and Appointments:

  • Assistant Professor, Department of Immunology
  • Adjunct Professor, Department of Medical Microbiology

Education:

  • B.Sc. (Honors) Microbiology, 1992 - University of Manitoba
  • Ph.D. Medical Microbiology, 1999 - University of Manitoba

Current Project:

Immunogenetics of antibody responses and vaccine development for infectious disease.

Research Interests: Dr. Berry's research interests are aimed at understanding the immunogenetics of antibody responses and vaccine development for infectious disease. A strong understanding of the immunogenetics of antibody responses to protective antigens on pathogenic microorganisms will allow new insights on host response and on the evolution of the immune system to be developed. These insights will be translated into practical real-world applications through improved methods of triggering protective antibody responses to that pathogen. It is obvious that improved methods for mAb development as well as a pool of personnel trained in classical and modern mAb development, are fundamental to, and will support breakthroughs in proteomics, research, and emerging infectious diseases therapy.


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Kristina Broliden

Email: Kristina.Broliden@ki.se

Trainings and Appointments:

  • Professor, Department of Clinical Virology, Karolinska Institute, Sweden

Education:

    MD, PhD

Current Project:

HIV-1 neutraling antibody responses and vaccine development

Research Interests: Despite all gaps in our knowledge of HIV/AIDS there are clear examples of protection against HIV-1 infection in both humans and primates. The most significant cases are represented by the highly-exposed persistently seronegative (HEPS) individuals who, by definition, are repeatedly exposed to HIV-1 over long periods of time but who resist infection. In an effort to better understand the mechanisms behind this resistance, we will analyse the humoral and innate immune responses in the mucosa of these individuals. This project will hopefully increase the understanding of HIV-1 pathogenesis with the specific aim to contribute to HIV-vaccine development


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Michael Eze

Email: m.eze@uwinnipeg.ca

Web: http://chemistry.uwinnipeg.ca/meze

Trainings and Appointments:

  • Visiting Scholar in Dr. Keith Fowke's laboratory, University of Manitoba
  • Associate Professor, Dept. of Chem., University of Winnipeg
  • Adjunct Professor, Dept. of Chem. University of Manitoba
  • Formerly, Professor of Biochemistry, University of Nigeria, Nsukka.
  • Group Leader, Tropical Diseases Research Group University of Nigeria 1991-1994

Education:

  • B.Sc. Nigeria
  • Ph.D. University of Alberta

Current Project:

Anti-viral Immunity

Research Interests:

  • The role of reactive oxygen species and nitric oxide in vital processes, especially in cellular immunity and pathogenesis in infectious disease states (e.g., malaria and brucellosis).
  • The effects of oxidative stress modulating chemical agents on fatty acid synthesis as well as on cerulenin (antibiotic) susceptibility in Escherichia coli and Azotobacter vinelandii.
  • Currently interested in, and engaged in HIV/AIDS research Dr. Keith Fowke’s laboratory.


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Rupert Kaul

Email: rupert.kaul@utoronto.ca

Trainings and Appointments:

  • Assistant Professor, Divisions of Infectious Disease and Clinical Science, Department of Medicine, University of Toronto.
  • Canada Research Chair in HIV, 2002. Full member, Institute of Medical Sciences, Department of Medicine, University of Toronto.

Education:

  • MD 1990 - University of Toronto
  • PhD Immunology 2002 - Open University, UK

Current Project:

Cellular immunology studies to determine patterns of immune responses to HIV.

Research Interests: Immune correlates of HIV susceptibility and transmission, with a focus on cellular immunity and genital tract immunology; immunological and clinical interactions between HIV and other sexually transmitted infections. As a medical doctor and a doctoral candidate in Immunology, Dr. Rupert Kaul has spent many years focusing on HIV-specific responses in the blood and genital tracts of highly exposed, persistently seronegative sex workers in Kenya.


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Nicolaas Nagelkerke

Email: nico.nagelkerke@uaeu.ac.ae

Trainings and Appointments:

  • (Full) professor of Biostatistics, Dept of Community Medicine, United Arab Emirates University, Al Ain, United Arab Emirates.2004
  • 1998 Sept-2000 March Biostatistician/epidemiologogist (1.5 days/week) with the Royal Netherlands Tuberculosis Association.

Education:

  • Drs. Mathematics - Leiden University
  • Ph.D. Biostatics - University of Amsterdam

Current Project:

Biostatistics in field of communicable diseases

Research Interests: Prof. Nico Nagelkerke joined the Department of Community Medicine as Senior Biostatistician in December 2004. He is previously from the University of Leiden in the Netherlands and received his full professorship as Professor of Statistical Methods in Public Health Research in April 2004. In addition to biostatistics, mathematics and epidemiology, Prof. Nagelkerke has expertise in the fields of communicable diseases (e.g. HIV/STD, TB) and non-communicable diseases such as cancer. The unique combination of expertise in biostatistics and in-depth knowledge of the medical or biological subjects for which the statistical analyses are made, has served to make his consultancy that more efficient and productive.


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Ken Rosenthal

Email: rosenthl@mcmaster.ca

Trainings and Appointments:

  • Professor Pathology and Molecular Medicine
  • Division Head, Molecular Medicine Head, Viral Vaccines Division
  • Past President, Canadian Association for HIV Research

Education:

  • B.Sc. University of Illinois, 1972
  • M.Sc. University of Illinios, 1974
  • Ph.D. McMaster University, 1978

Focus:

Mucosal immunity against viral infections

Research Interests: Recently news reports have been dominated by stories concerning infections with SARS, West Nile virus and Mad Cow disease. With the continued spread of HIV/AIDS, especially in developing countries, we are also experiencing the worst epidemic in human history. For a number of years our group has been interested in understanding mucosal immune responses and protection against mucosal viral infections. Indeed, most viruses initiate infection at mucosal surfaces of the respiratory, digestive and genital tracts and these surfaces are protected by a separate and less-well understood mucosal immune system. We have been studying the role of innate and adaptive mucosal immune responses, especially against sexually-transmitted infections, including herpes simplex virus type 2 (HSV-2) and HIV. Recently, along with a number of other investigators at McMaster, we formed and received support for a ‘CIHR Group in Mucosal Immunity.’ This Group is focused on understanding the mechanisms by which the innate mucosal immune system identifies and controls infections of the lung, gut and genital tract, and characterize the innate response’s influence on adaptive mucosal immunity.


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Rafick Sekaly

Email: rafick-pierre.sekaly@umontreal.ca

Trainings and Appointments:

  • Adjunct Professor; Immunology - Faculty of Medicine, McGill University
  • Project Leader, Functional Genomics, Pharmacogenomics and Proteomics of the Immune Response in Health and Immune Related Disorders

Education:

  • M.Sc. - University de Montreal
  • D.Sc. - Lausanne

Current Project:

Molecular interactions between surface molecules involved in T-cell activation

Research Interests:


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