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Technicians | Fellows | Students | Former Lab Members | Honours

Technicians


Steve Wayne

Email: waynesa@ms.umanitoba.ca

Supervisor:

Dr. Keith Fowke

Position:

Technician

Degrees obtained:

  • B.Sc. Microbiology - University of Manitoba

Current Project:

Tech Support

About: Steve is a research technician for Dr. Keith Fowke. He has a 4 year BSc. major in microbiology from the University of Manitoba. Steve provides tech support and have been involved in many projects that include many techniques. This includes molecular biology, cytometry, cell culture, and other protocols. I also run and overlook our BD FACScailbur cytometer and Epics Elite sorter in level 3. He has recently begun using Luminex bead technology to study samples.

Andrew Stalker

Email: atstalker@gmail.com

Supervisor:

Dr. Keith Fowke

Position:

Technician

Degrees obtained:

  • B.Sc. (Hons.) Genetics -
    University of Manitoba

Current Project:

SNP detection and analysis through gene sequencing

About: Andrew is a new technician to the Fowke lab. His major focus is assisting with molecular biology and genetics based projects.


Fellows

Yoav Keynan

Email: Keynany@yahoo.com

Supervisor:

Dr. Keith Fowke

Position:

Clinical Fellow and
PhD Candidate

Degrees obtained:

  • Doctor of Medicine- Faculty of Health Sciences, Ben-Gurion University of the Negev
  • 1999-2004 –Residency- Division of Medicine - Carmel Medical Center- Haifa, Israel.

Current Project:

Using suspension bead array for antibody detection and flow-cytometry for CMI

About: Using suspension bead array for antibody detection and flow-cytometry for CMI the antigen specific responses to HIV and Influenza are determined. The influenza and HIV specific responses of HIV resistant commercial sex workers will be determined before and after mucosal influenza vaccine challenge

Julie Lajoie

Email:

Supervisor:

Dr. Keith Fowke

Position:

Postdoctoral Fellow

Degrees obtained:

  • M.Sc. Microbiology -
    Université de Montréal
  • Research Assistant -
    Laboratoire d'immunogénétique
  • PhD. Virology -
    Université de Montréal

Current Project:

Study of the mucosal immunology in highly exposed seronegative commercial sex workers

About: The majority of new HIV infection occurs via heterosexual transmission. Understanding the factors influencing the susceptibility/protection to HIV infection is important in order to develop a safe and efficient compound to prevent HIV infection. Despite to be at high risk of HIV acquisition, some individuals remain HIV uninfected. This study aims to understanding the immune factor at the female genital tract compartment that might explain this protection against HIV infection.

Genevieve Boily-Larouche

Email: genevieve.boily.larouche@gmail.com

Supervisor:

Dr. Keith Fowke

Position:

Postdoctoral Fellow

Degrees obtained:

  • PhD. Virology and Immunology -
    University of Montreal

Current Project:

Longitudinal analysis of mucosal immune quiescence study

About: Pumwani Sex Worker Cohort of Nairobi, Kenya contained small sub-group of women who are intensively exposed to HIV-1 yet remained uninfected. Previous studies from HIV resistant commercial sex workers have provided strong evidences of an immunologically quiescent phenotype among these women. Multiple factors may drive immune quiescence in HIV Exposed Seronegative (HESN) sex workers and contribute to reduce their susceptibility to HIV infection. Sex work results in exposure to very strong immune stimulants and affects the level of immune activation. This project will study the impact of sex work on peripheral and mucosal immunological factors in a longitudinal analysis of mucosal immune quiescence.


Students


Jennifer Juno

Email: umjuno@cc.umanitoba.ca

Supervisor:

Dr. Keith Fowke

Position:

PhD Candidate

Degrees obtained:

  • B.Sc.(Hons.) Molecular Biology -
    University of Toronto

Current Project:

Impact of Genetic Variation at the CD4 Locus on HIV Susceptibility and Disease Progression

About: Our lab has previously identified a polymorphism in the CD4 gene that is associated with increased susceptibility to HIV infection and accelerated disease progression. A nearby gene, GNB3, mediates signaling cascades initiated by the HIV co-receptors CCR5 and CXCR4 and contains multiple polymorphisms that regulate its function. The CD4 gene is also in close proximity to LAG-3 (Lymphocyte activation gene 3), a T cell activation and exhaustion marker whose role in HIV infection is not well described. This project will investigate whether the GNB3 825T polymorphism is associated with HIV susceptibility or disease progression among high- and low-risk Kenyan women, and will characterize the expression and function of LAG-3 on immune subsets during HIV infection and ARV therapy.

Courtney Bell

Email: umbell4@cc.umanitoba.ca

Supervisor:

Dr. Keith Fowke

Position:

M.Sc. Graduate Student

Degrees obtained:

  • B.Sc. (Hons.) Biology -
    University of Winnipeg
  • B.Sc. Biochemistry -
    University of Winnipeg

Current Project:

 

About:

Abdi Abdullahi

Email: aabdul03@gmail.com

Supervisor:

Dr. Keith Fowke

Position:

M.Sc. Graduate Student

Degrees obtained:

  • B.Sc.Microbiology -
    University of Manitoba

Current Project:

Investigation of Immune Quiescence: Assessing the role of T regulatory cells a in HIV Exposed Sero-negative (HESN) subjects

About: Tregs are a subset of CD4+ cells that have important roles in central tolerance and maintenance of homeostasis of immune cells. They have been shown to suppress CD4+ and CD8+ T cells responses to HIV and other antigens. Recently it has been shown that HIV resistant women have higher levels of CD4+CD25+FOXP3+ Tregs compared to HIV-susceptible women. The focus on my project will be to assess the role of Tregs in the Immune Quiescence model of resistance, which suggests that a reduced activation state is protective against HIV infection. To assess if elevated Tregs are contributing to the Immune Quiescent phenotype in HIV resistant women, Tregs will be depleted from PBMCs and analyzed for activation, proliferation and cytokine expression by flow cytometry following stimulation with different activating agents .We hypothesize Treg depletion will result in higher activation, proliferation and cytokine responses, suggesting that Tregs have a suppressive role in HIV resistant women and thus might be contributing to Immune Quiescence.



Former Lab Members

Catherine Card

Supervisor:
Dr. Keith Fowke
Position:
Student
Term:
2005 - 2012
Degrees obtained:
  • PhD - University of Manitoba
Project:
The role of regulatory T cells in HIV infection and resistance
Outcome:
PDF at University of Lausanne, Switzerland

Paul McLaren

Supervisor:
Dr. Keith Fowke
Position:
Student
Term:
2000 - 2008
Degrees obtained:
  • M.Sc. - University of Manitoba
  • PhD - University of Manitoba
Project:
The role of regulatory T cells in HIV infection and resistance
Outcome:
PDF at Harvard Medical School

Conar O'Neil

Supervisor:
Dr. Keith Fowke
Position:
Summer Student
Term:
2006 - 2008
Project:
CD4 Polymorphism Detection Optimization
Influenza Antibody Responses
Outcome:
Entered Med School

Sandra Koesters

Email: umkoest0@cc.umanitoba.ca

Supervisor:
Dr. Keith Fowke
Position:
Student
Term:
2000 - 2007
Degrees obtained:
  • M.Sc. - University of Manitoba
  • PhD - University of Manitoba
Project:
Mechanisms of HIV disease progression
Outcome:
Research Scientist - National Microbiology Labs

Michael Eze

Email: m.eze@uwinnipeg.ca

Supervisor:
Dr. Keith Fowke
Position:
Visiting Scholar
Term:
2006 - 2007
Project:
Anti-viral Immunity
Home Institution:
University of Winnipeg
Interests:
  • The role of reactive oxygen species and nitric oxide in vital processes, especially in cellular immunity and pathogenesis in infectious disease states (e.g., malaria and brucellosis).
  • The effects of oxidative stress modulating chemical agents on fatty acid synthesis as well as on cerulenin (antibiotic) susceptibility in Escherichia coli and Azotobacter vinelandii.
  • Currently interested in, and engaged in HIV/AIDS research with Dr. Keith Fowke’s laboratory.

Stu Skinner

Supervisor:
Dr. Keith Fowke
Position:
Clinical Fellow
Term:
2006 - 2007
Project:
Assessment of humoral immune responses to HIV elite controllers
Outcome:
Assistant Professor, Dept. of Medicine -
University of Saskachewan

Francoise Vouriot

Supervisor:
Dr. Keith Fowke
Position:
M.Sc. Student
Term:
2002-2005
Honours:
  • 2002/4 NSERC National Studentship - $17,300
  • 2003 Faculty of Graduate Studies Travel Award
  • 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
  • 2005 Manitoba Medical Service Foundation Award for Excellence in Research by a Masters student. $1000.
Project:
Exploring the role of CD4 868T in mother to child transmission of HIV
Outcome:
High School Science Teacher

Judie Alimonti

Supervisor:
Dr. Keith Fowke
Position:
Postdoctoral Fellow
Term:
2001-2005
Honours:
  • 2001 MHRC Fellowship
  • 2001/03 CIHR Postdoctoral Fellowship $35,000/yr
  • 2002 admitted to the ICID/CIHR National Training Program in Infectious Diseases
Project:
Defining HIV-specific CD4+ T-helper epitopes in HIV-resistant and HIV-infected individuals.
Outcome:
Research Biologist - National Microbiology Lab

Jennifer Athayde

Supervisor:
Dr. Keith Fowke
Position:
B.Sc. Medicine Student
Term:
2002-2004
Honours:
  • 2004 Morris Newman Memorial Award for First Term B.Sc.(Med) Presentation $1000
Project:
Determine the role of immunoglobulin G subtypes in HIV disease progression.
Outcome:
Graduated

Other Former Lab Members

  • Jon Bellas - 2000-2001
  • Jared Bullard - 2001-2002
  • Tamar Davis - 2005
  • Makobu Kimani - 2002
  • Sarah Myk - 2001-2003
  • Mariel Plummer - 2002-2003

Honours


Ms. Catherine Card

  • 2005/6 Manitoba Health Research Council Studentship $17,850
  • 2006-07 CIHR Graduate Student Award-Master's
  • 2006 Poster Presentation Award-International Centre for Infectious Disease Retreat
  • 2007 Public Health Agency of Canada Research Forum Best Student Poster Award
  • 2007 First Place Award for Dept of Medical Microbiology Journal Club Presentaiton
  • 2007-10 CIHR Graduate Student Award-PhD

Ms. Sandra Koesters

  • 2000/2001 The Ade and Co. Award for Outstanding Journal Club Presentation
  • 2001/02 Allan Ronald Graduate Fellowship - $7,000
  • 2001 Faculty of Graduate Studies Travel Award
  • 2002/04 Manitoba Health Research Council Graduate Fellowship - $16,000
  • 2002- admitted to the ICID/CIHR National Training Program in Infectious Diseases
  • 2003-2006 CIHR Doctoral Research Award
  • 2003 Canada Student Health Research Forum – Manitoba Poster Competition Prize
  • 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
  • 2007 Manitoba Medical Services Foundation Major Award for PhD Thesis in Medicine

Mr. Paul McLaren

  • 2000 Health Sciences Centre Foundation Studentship $15,000
  • 2001/2 University of Manitoba Graduate Fellowship – declined
  • 2001/03 Manitoba Health Research Council Graduate Fellowship - $16,000
  • 2002- admitted to the ICID/CIHR National Training Program in Infectious Diseases
  • 2002/2003 The Ade and Co. Award for Outstanding Journal Club Presentation
  • 2003-2006 CIHR Doctoral Research Award
  • 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
  • 2006 Oral Presentation Award-International Centre for Infectious Disease Retreat

Mr. Julias Oyugi

  • 2004/5 Manitoba Health Research Council Studentship $17,850
  • 2004 Admitted to CIHR/International Centre for Infectious Disease National Training Program
  • 2006 Public Health Agency of Canada National Conference - Poster Prize Winner $250
  • 2006 New Investigator Award – Basic Science Category. Canadian Association for HIV Research Annual Meeting 2006, $1000
  • 2006-07 Health Sciences Centre foundation Graduate Scholarship
  • 2006 Poster Presentation Award-International Centre for Infectious Disease Retreat

Ms. Jennifer Juno

  • 2011 University of Manitoba Research Days Poster Award
  • 2010 Abstract Award; Canadian Conference on HIV/AIDS Research
  • 2009 CIHR Vanier Scholarship University of Manitoba Research Days Poster Award
  • 2008 NSERC PGS M Scholarship - Honourable Mention -
    University of Manitoba Research  Days Poster Competition
  • 2007-08 National Science and Engineering Research Council (NSERC) Canada Graduate Sholarship (CGS M)
  • 2007 NSERC CGS M Scholarship - Top Undergraduate Thesis Oral Presentation Award - Outstanding Undergraduate Research Project 
  • 2006 NSERC Undergraduate Student Research Award
  • 2005 NSERC Undergraduate Student Research Award

Mr. Jonothan Bellas

  • 2000 Morris Newman Memorial Award for First Term B.Sc. (Med) Presentation
  • 2001 Award for Excellence in B.Sc. (Med) final presentation

Ms. Jared Bullard

  • 2001 Morris Newman Memorial Award for First Term B.Sc. (Med) Presentaion
  • 2002 Merck Sharp & Dohme Scholarship for Best Basic Science Project
  • 2002 National Student Research Forum Tracel Award to Galveston 2003
  • 2002 Nicholson Prize for Best Overall Project

Ms. Jennifer Athayde

  • 2004 Morris Newman Memorial Award for First Term B.Sc.(Med) Presentation

Mr. Tavis Bodnarchuk

  • 2007 Mr. Justice James E. Wilson Award for outstanding performance in the first year of BSc (Med) program.

Ms. Francoise Vouroit

  • 2002/4 NSERC National Studentship
  • 2003 Faculty of Graduate Travel Award
  • 2004 Canada Student Health Research Forum-Manitoba Poster Competition Prize
  • 2005 Manitoba Medical Service Foundation Award for Excellence in Research by a Master student

Mr. Tavis Bodnarchuk

  • 2007 Mr. Justice James E. Wilson Award for outstanding performance in the first year of BSc (Med) program.

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Page last modified: 17/05/2012